# CA125 blood test and ultrasound for ovarian cancer

> Source: World Aid Network — https://worldaidnetwork.org/cancer/ovarian-cancer/tests

## In short

If ovarian cancer is possible, a GP may order a CA125 blood test and a pelvic ultrasound. A raised CA125 has many causes besides cancer, including endometriosis and infection. A normal CA125 does not completely rule cancer out if symptoms continue. Go back to the GP if you are still unwell.

These tests start a pathway. They are not a yes-or-no home kit. Specialists may add CT, MRI and surgery.

## What does CA125 measure?

CA125 can be raised in ovarian cancer, especially later-stage epithelial disease. It also rises in pregnancy, periods, fibroids and endometriosis. It is not used to screen well women at average risk.

## What if tests are normal but symptoms continue?

Ask for a review. Persistent symptoms after normal tests still deserve another look.

## Who needs closer surveillance?

BRCA1 and BRCA2 changes raise ovarian as well as breast cancer risk. Some women choose risk-reducing surgery after genetic counselling.

## Key takeaways

- CA125 plus ultrasound is a GP first step, not a public screening programme.
- A raised CA125 has many non-cancer causes.
- Persistent symptoms after normal tests still deserve a second look.
- BRCA gene changes can mean extra options after counselling.

## Related pages in this guide

- Overview: https://worldaidnetwork.org/cancer/ovarian-cancer
- Symptoms: https://worldaidnetwork.org/cancer/ovarian-cancer/symptoms
- CA125 & scans: https://worldaidnetwork.org/cancer/ovarian-cancer/tests
- Treatment options: https://worldaidnetwork.org/cancer/ovarian-cancer/treatment

## Frequently asked questions

### Can I buy CA125 privately and skip the GP?

A number alone is easy to misread. Abnormal results still need a clinician who can examine you and arrange ultrasound.

### Does a normal ultrasound mean I am fine?

It is reassuring but not perfect. If symptoms continue, ask the GP to think again.

### Is there screening if my mother had ovarian cancer?

A GP can take a family history and refer to genetics if criteria are met. That is not a national screening programme.

## How you can help

World Aid Network funds cancer treatment for patients who cannot pay in Pakistan, Indonesia and Malaysia. Donate at https://worldaidnetwork.org/appeal/cancer-emergency or https://worldaidnetwork.org/donate?cause=cancer-treatment&appeal=cancer-emergency

---
This is general information, not medical advice, published by World Aid Network. Always consult a qualified clinician about your own health.